Nature · Cover story
PsychAD makes the cover of Nature
Our population-scale atlas opens a new window into the human brain, across eight disorders.
From the Lee Lab
Discoveries & milestones.
New science, shared achievements and stories from our community.
September 2026
Two covers. One remarkable month.
Nature Genetics · Cover story
FreshMG on the cover of Nature Genetics
Revealing the remarkable plasticity of the brain’s immune cells in aging and Alzheimer’s disease.
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FreshMG is out in Nature Genetics
A map of 832,505 human microglia and perivascular macrophages from 1,607 donors, and a protective microglia state that depends on TREM2.
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Preprint: gene regulatory programs of cognitive resilience
Collin Spencer leads a new preprint on why some people keep their memory despite Alzheimer's pathology.
Research
The PsychAD dataset is published in Scientific Data
Genotypes and single-nucleus transcriptomes from 6.3 million nuclei and 1,494 donors, openly available.
Research
Tereza Clarence's postnatal brain study in Nature Genetics
Joint gene expression and chromatin profiling of 101,924 nuclei maps the regulators of brain development from infancy to late adulthood.