Opportunities at Lee Lab

Bring your curiosity.
Make your discovery.

We welcome postdocs and graduate students who want to understand the brain through computation, genetics and single-cell biology.

Why join us

Important questions.
Room to make them yours.

How do cells become vulnerable to disease? Why do some people remain cognitively resilient? Which genetic changes matter, and in which cells? Our datasets open the door to questions that span the full complexity of the human brain.

At the Lee Lab, you’ll work at the intersection of computational methods and biological discovery, within the collaborative Center for Disease Neurogenomics at Mount Sinai.

How to get in touch ↓

Open opportunities

Find your next chapter.

Accepting inquiries

Postdoctoral fellow

Computational postdocs with a PhD in computational biology, statistics, computer science, genetics, neuroscience or a related field.

Get in touch
Accepting inquiries

PhD rotation

Icahn Mount Sinai PhD students in any training area. Email Donghoon to set up a rotation.

Get in touch

Opportunities updated September 2026. MD/PhD students interested in the lab are also welcome to contact us.

Your research environment

Build the skills to ask more.

01

Data with depth

Work with population-scale human brain data: 6.3 million nuclei in PsychAD and more than 832,000 immune cells in FreshMG.

02

Methods that matter

Develop expertise in single-cell analysis, statistical genetics, machine learning and reproducible computational research.

03

A connected community

Collaborate across the Center for Disease Neurogenomics, with access to Mount Sinai’s research community and Minerva computing resources.

Trainees at the forefront

Your contribution
can lead the story.

Our students and postdocs play leading roles in the lab’s research.

Postdoctoral research · Nature Genetics, 2025

Tereza Clarence

First and co-corresponding author on a multiomic study of gene regulation in the postnatal human brain.

Read the study

Graduate research · Nature Genetics, 2026

Christian Porras & Collin Spencer

Co-first authors of FreshMG, featured on the September cover of Nature Genetics.

Read the cover story

Start a conversation

Tell us what
you’re curious about.

Send your CV and a brief introduction describing your research experience and the questions you’d like to pursue. Links to publications or code are welcome.

Email admin@leelab.us

For prospective postdocs

We welcome backgrounds in computational biology, statistics, computer science, genetics, neuroscience and related fields. Use “Postdoc inquiry” and your name in the subject line.

For graduate students

Current Icahn Mount Sinai students can contact Donghoon about a rotation. Prospective students should apply through the relevant graduate program and mention their interest in our research.

See program websites for current admissions requirements and deadlines.